1. 

Relation of MRI visible perivascular spaces with global and regional brain structural connectivity measures: The Framingham Heart Study (FHS). 

Ekenze O, Seiler S, Pinheiro A, DeCarli C, Parva P, Habes M, Charidimou A, Maillard P, Beiser A, Seshadri S, Demissie S, Romero JR.

Neurobiol Aging. 2025 Jun;150:1-8. doi: 10.1016/j.neurobiolaging.2025.02.007. Epub 2025 Feb 27.

PMID: 40043467 

2. 

Multimodal Associations of Modifiable Risk Factors on White Matter Injury: The SOL-INCA-MRI Study (HCHS/SOL). 

Sapkota S, Maillard P, Stickel AM, Tarraf W, González KA, Ivanovic V, Morlett-Paredes A, Cai J, Isasi CR, Lipton RB, Daviglus M, Testai FD, Lamar M, Gallo LC, Talavera GA, Agudelo C, Ramos AR, González HM, DeCarli C.

Stroke. 2025 May;56(5):1138-1148. doi: 10.1161/STROKEAHA.124.049904. Epub 2025 Mar 24.

PMID: 40123500 Free PMC article. 

3. 

Association of Cardiovascular Health With Brain Volume and White Matter Integrity: Results of the SOL-INCA MRI Study. 

Trifan G, Stickel AM, Cai J, Daviglus M, Estrella M, Garcia-Bedoya O, Gallo LC, Isasi CR, Kaplan R, Lamar M, Talavera GA, Tarraf W, Gonzalez HM, Maillard P, Decarli CS, Testai FD.

Neurology. 2025 Apr 22;104(8):e213404. doi: 10.1212/WNL.0000000000213404. Epub 2025 Mar 24.

PMID: 40127389 

4. 

Depressive symptoms are associated with hippocampal volume in the oldest-old: The LifeAfter90 study. 

Posis AIB, Rojas-Saunero LP, Lor Y, George KM, Gilsanz P, Maillard P, Corrada MM, Whitmer RA.

Psychiatry Res Neuroimaging. 2025 Apr;348:111967. doi: 10.1016/j.pscychresns.2025.111967. Epub 2025 Feb 19.

PMID: 39999633 

5. 

Healthy dietary intake diminishes the effect of cerebral small vessel disease on cognitive performance in older adults. 

Bauer CE, Zachariou V, Pappas C, Maillard P, DeCarli C, Caprihan A, Gold BT.

Front Neurol. 2025 Mar 6;16:1508148. doi: 10.3389/fneur.2025.1508148. eCollection 2025.

PMID: 40115382 Free PMC article. 

6. 

WMH Contributions to Cognitive Impairment: Rationale and Design of the Diverse VCID Study. 

DeCarli C, Rajan KB, Jin LW, Hinman J, Johnson DK, Harvey D, Fornage M; Diverse VCID Study Investigators.

Stroke. 2025 Mar;56(3):758-776. doi: 10.1161/STROKEAHA.124.045903. Epub 2024 Nov 15.

PMID: 39545328 Review. 

7. 

Sex-Specific Vulnerabilities to Subclinical Vascular Brain Injury in Early Late-Life: The Framingham Heart Study. 

Yau WW, Scott MR, Petrea RE, Buckley RF, Kojis D, Sperling RA, Chhatwal JP, Maillard P, Aparicio HJ, Romero JR, DeCarli CS, Beiser AS, Seshadri S.

Ann Neurol. 2025 Mar;97(3):460-469. doi: 10.1002/ana.27135. Epub 2024 Nov 14.

PMID: 39540324 

8. 

Extended Technical and Clinical Validation of Deep Learning-Based Brainstem Segmentation for Application in Neurodegenerative Diseases. 

Gesierich B, Sander L, Pirpamer L, Meier DS, Ruberte E, Amann M, Sinnecker T, Huck A, de Leeuw FE, Maillard P, Moy S, Helmer KG; MarkVCID Consortium; Levin J, Höglinger GU; PROMESA Study Group; Kühne M, Bonati LH, Kuhle J, Cattin P, Granziera C, Schlaeger R, Duering M.

Hum Brain Mapp. 2025 Feb 15;46(3):e70141. doi: 10.1002/hbm.70141.

PMID: 39936343 Free PMC article. 

9. 

MRI free water mediates the association between diffusion tensor image analysis along the perivascular space and executive function in four independent middle to aged cohorts. 

Liu X, Maillard P, Barisano G, Caprihan A, Cen S, Shao X, Jann K, Ringman JM, Lu H, Arfanakis K, DeCarli CS, Gold BT, Seshadri S, Satizabal CL, Beiser AS, Habes M, Kramer JH, Stables L, Singh H, Helmer KG, Greenberg SM, Wang DJJ; MarkVCID Consortium.

Alzheimers Dement. 2025 Feb;21(2):e14453. doi: 10.1002/alz.14453. Epub 2024 Dec 30.

PMID: 39740225 Free PMC article. 

10. 

White matter free water mediates the associations between placental growth factor, white matter hyperintensities, and cognitive status. 

Kern KC, Vohra M, Thirion ML, Wang DJJ, Wilcock DM, Thompson JF, Rosenberg GA, Sagare A, Moghekar A, Lu H, Lee T, Elahi FM, Satizabal CL, Tracy R, Seshadri S, Schwab K, Helmer K, Singh H, Kivisäkk P, Greenberg SM, Vossel K, Kramer JH, Maillard P, DeCarli CS, Hinman JD.

Alzheimers Dement. 2025 Feb;21(2):e14408. doi: 10.1002/alz.14408. Epub 2024 Dec 18.

PMID: 39692213 Free PMC article. 

11. 

Cerebral white matter hyperintensity volumes: Normative age- and sex-specific values from 15 population-based cohorts comprising 14,876 individuals. 

de Kort FAS, Vinke EJ, van der Lelij EJ, Anblagan D, Bastin ME, Beiser A, Brodaty H, Chaturvedi N, Cheng B, Cox SR, DeCarli C, Enzinger C, Fletcher E, Frayne R, de Groot M, Huang F, Ikram MA, Jiang J, Lam BYK, Maillard P, Mayer C, McCreary CR, Mok V, Maniega SM, Petersen M, Roshchupkin G, Sachdev PS, Schmidt R, Seiler S, Seshadri S, Sudre CH, Thomalla G, Twerenbold R, Valdés Hernández M, Vernooij MW, Wardlaw JM, Wen W, Kuijf HJ, Biessels GJ, Biesbroek JM.

Neurobiol Aging. 2025 Feb;146:38-47. doi: 10.1016/j.neurobiolaging.2024.11.006. Epub 2024 Nov 20.

PMID: 39602940 Free PMC article. 

12. 

Associations between cerebral blood flow and progression of white matter hyperintensities. 

Thammasart S, Harvey DJ, Maillard P, DeCarli C, Donnay CA, Wheeler GJ, Fan AP.

Front Neuroimaging. 2025 Jan 21;3:1463311. doi: 10.3389/fnimg.2024.1463311. eCollection 2024.

PMID: 39906355 Free PMC article. 

13. 

Tract-specific white matter hyperintensities and neuropsychiatric syndromes: a multicentre memory clinic study. 

Kan CN, Coenen M, Xu X, Hilal S, Barkhof F, Benke T, Dal-Bianco P, DeCarli C, Duering M, Enzinger C, Exalto LG, Fletcher EF, Hofer E, Koek HL, Kuijf HJ, Maillard PM, Moonen JEF, Papma JM, Pijnenburg YAL, Schmidt R, Steketee RME, van den Berg E, van der Flier WM, Venketasubramanian N, Vernooij MW, Wolters FJ, Biessels GJ, Chen CL, Biesbroek JM, Tan CH; Alzheimer’s Disease Neuroimaging Initiative.

J Neurol Neurosurg Psychiatry. 2025 Jan 6:jnnp-2024-334264. doi: 10.1136/jnnp-2024-334264. Online ahead of print.

PMID: 39761997 

14. 

The POINTER Imaging baseline cohort: Associations between multimodal neuroimaging biomarkers, cardiovascular health, and cognition. 

Harrison TM, Ward T, Taggett J, Maillard P, Lockhart SN, Jung Y, Lovato LC, Koeppe R, Jagust WJ, Harvey D, Masdeu JC, Oh H, Gitelman DR, Aggarwal NT, Espeland MA, Cleveland ML, Whitmer R, Farias ST, Salloway S, Pavlik V, Yu M, Tangney C, Snyder H, Carrillo M, Baker LD, Vemuri P, DeCarli C, Landau SM; U.S. POINTER Study Group.

Alzheimers Dement. 2025 Jan;21(1):e14399. doi: 10.1002/alz.14399. Epub 2024 Dec 6.

PMID: 39641363 Free PMC article. 

15. 

Enhancing cognitive performance prediction by white matter hyperintensity connectivity assessment. 

Petersen M, Coenen M, DeCarli C, De Luca A, van der Lelij E; Alzheimer’s Disease Neuroimaging Initiative; Barkhof F, Benke T, Chen CPLH, Dal-Bianco P, Dewenter A, Duering M, Enzinger C, Ewers M, Exalto LG, Fletcher EM, Franzmeier N, Hilal S, Hofer E, Koek HL, Maier AB, Maillard PM, McCreary CR, Papma JM, Pijnenburg YAL, Schmidt R, Smith EE, Steketee RME, van den Berg E, van der Flier WM, Venkatraghavan V, Venketasubramanian N, Vernooij MW, Wolters FJ, Xu X, Horn A, Patil KR, Eickhoff SB, Thomalla G, Biesbroek JM, Biessels GJ, Cheng B.

Brain. 2024 Dec 3;147(12):4265-4279. doi: 10.1093/brain/awae315.

PMID: 39400198 Free PMC article. 

16. 

Biological validation of peak-width of skeletonized mean diffusivity as a VCID biomarker: The MarkVCID Consortium. 

Luckey AM, Ghosh S, Wang CP, Beiser A, Bernal R, Li Z, Mbangdadji D, Fadaee E, Snoussi H, Dediós AGV, Trevino HA, Goss M, Hillmer LJ, Bauer CE, Staffaroni AM, Stables L, Albert M, Himali JJ, Mosley TH, Forsberg L, Guðnason V, Singh B, Singh H, Schwab K, Kramer JH, Rosenberg GA, Helmer KG, Greenberg SM, Habes M, Wang DJJ, Gold BT, Lu H, Caprihan A, Fornage M, Launer LJ, Arfanakis K, Seshadri S, DeCarli C, Maillard P, Satizabal CL.

Alzheimers Dement. 2024 Dec;20(12):8814-8824. doi: 10.1002/alz.14345. Epub 2024 Nov 21.

PMID: 39569745 Free PMC article. 

17. 

Cerebrovascular markers of WMH and infarcts in ADNI: A historical perspective and future directions. 

Maillard P, Fletcher E, Carmichael O, Schwarz C, Seiler S, DeCarli C; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2024 Dec;20(12):8953-8968. doi: 10.1002/alz.14358. Epub 2024 Nov 13.

PMID: 39535353 Free PMC article. Review. 

18. 

Sexually dimorphic differences in angiogenesis markers are associated with brain aging trajectories in humans. 

Torres-Espin A, Radabaugh HL, Treiman S, Fitzsimons SS, Harvey D, Chou A, Lindbergh CA, Casaletto KB, Goldberger L, Staffaroni AM, Maillard P, Miller BL, DeCarli C, Hinman JD, Ferguson AR, Kramer JH, Elahi FM.

Sci Transl Med. 2024 Nov 27;16(775):eadk3118. doi: 10.1126/scitranslmed.adk3118. Epub 2024 Nov 27.

PMID: 39602511 Free PMC article. 

19. 

Childhood Community Disadvantage and MRI-Derived Structural Brain Integrity After Age 65 Years. 

Peterson RL, Meza E, George KM, Maillard P, DeCarli C, Gilsanz P, Soh Y, Lor Y, Kind AJ, Barnes LL, Whitmer RA.

JAMA Netw Open. 2024 Nov 4;7(11):e2443703. doi: 10.1001/jamanetworkopen.2024.43703.

PMID: 39509129 Free PMC article. 

20. 

Circulating adipokines and MRI markers of brain aging in middle-aged adults from the community. 

Satizabal CL, Himali JJ, Conner SC, Beiser AS, Maillard P, Vasan RS, DeCarli C, Seshadri S.

J Alzheimers Dis. 2024 Nov;102(2):449-458. doi: 10.1177/13872877241289043. Epub 2024 Oct 29.

PMID: 39625328 Free PMC article. 

21. 

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries. 

García-Marín LM, Campos AI, Diaz-Torres S, Rabinowitz JA, Ceja Z, Mitchell BL, Grasby KL, Thorp JG, Agartz I, Alhusaini S, Ames D, Amouyel P, Andreassen OA, Arfanakis K, Arias-Vasquez A, Armstrong NJ, Athanasiu L, Bastin ME, Beiser AS, Bennett DA, Bis JC, Boks MPM, Boomsma DI, Brodaty H, Brouwer RM, Buitelaar JK, Burkhardt R, Cahn W, Calhoun VD, Carmichael OT, Chakravarty M, Chen Q, Ching CRK, Cichon S, Crespo-Facorro B, Crivello F, Dale AM, Smith GD, de Geus EJC, De Jager PL, de Zubicaray GI, Debette S, DeCarli C, Depondt C, Desrivières S, Djurovic S, Ehrlich S, Erk S, Espeseth T, Fernández G, Filippi I, Fisher SE, Fleischman DA, Fletcher E, Fornage M, Forstner AJ, Francks C, Franke B, Ge T, Goldman AL, Grabe HJ, Green RC, Grimm O, Groenewold NA, Gruber O, Gudnason V, Håberg AK, Haukvik UK, Heinz A, Hibar DP, Hilal S, Himali JJ, Ho BC, Hoehn DF, Hoekstra PJ, Hofer E, Hoffmann W, Holmes AJ, Homuth G, Hosten N, Ikram MK, Ipser JC, Jack CR Jr, Jahanshad N, Jönsson EG, Kahn RS, Kanai R, Klein M, Knol MJ, Launer LJ, Lawrie SM, Hellard SL, Lee PH, Lemaître H, Li S, Liewald DCM, Lin H, Longstreth WT Jr, Lopez OL, Luciano M, Maillard P, Marquand AF, Martin NG, Martinot JL, Mather KA, Mattay VS, McMahon KL, Mecocci P, Melle I, Meyer-Lindenberg A, Mirza-Schreiber N, Milaneschi Y, Mosley TH, Mühleisen TW, Müller-Myhsok B, Maniega SM, Nauck M, Nho K, Niessen WJ, Nöthen MM, Nyquist PA, Oosterlaan J, Pandolfo M, Paus T, Pausova Z, Penninx BWJH, Pike GB, Psaty BM, Pütz B, Reppermund S, Rietschel MD, Risacher SL, Romanczuk-Seiferth N, Romero-Garcia R, Roshchupkin GV, Rotter JI, Sachdev PS, Sämann PG, Saremi A, Sargurupremraj M, Saykin AJ, Schmaal L, Schmidt H, Schmidt R, Schofield PR, Scholz M, Schumann G, Schwarz E, Shen L, Shin J, Sisodiya SM, Smith AV, Smoller JW, Soininen HS, Steen VM, Stein DJ, Stein JL, Thomopoulos SI, Toga AW, Tordesillas-Gutiérrez D, Trollor JN, Valdes-Hernandez MC, van T Ent D, van Bokhoven H, van der Meer D, van der Wee NJA, Vázquez-Bourgon J, Veltman DJ, Vernooij MW, Villringer A, Vinke LN, Völzke H, Walter H, Wardlaw JM, Weinberger DR, Weiner MW, Wen W, Westlye LT, Westman E, White T, Witte AV, Wolf C, Yang J, Zwiers MP, Ikram MA, Seshadri S, Thompson PM, Satizabal CL, Medland SE, Rentería ME.

Nat Genet. 2024 Nov;56(11):2333-2344. doi: 10.1038/s41588-024-01951-z. Epub 2024 Oct 21.

PMID: 39433889 

22. 

Implementation and validation of face de-identification (de-facing) in ADNI4. 

Schwarz CG, Choe M, Rossi S, Das SR, Ittyerah R, Fletcher E, Maillard P, Singh B, Harvey DJ, Malone IB, Prosser L, Senjem ML, Matoush LC, Ward CP, Prakaashana CM, Landau SM, Koeppe RA, Lee J, DeCarli C, Weiner MW, Jack CR Jr, Jagust WJ, Yushkevich PA, Tosun D; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2024 Nov;20(11):8048-8061. doi: 10.1002/alz.14303. Epub 2024 Oct 11.

PMID: 39392215 Free PMC article. 

23. 

Overview of ADNI MRI. 

Jack CR Jr, Arani A, Borowski BJ, Cash DM, Crawford K, Das SR, DeCarli C, Fletcher E, Fox NC, Gunter JL, Ittyerah R, Harvey DJ, Jahanshad N, Maillard P, Malone IB, Nir TM, Reid RI, Reyes DA, Schwarz CG, Senjem ML, Thomas DL, Thompson PM, Tosun D, Yushkevich PA, Ward CP, Weiner MW; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2024 Oct;20(10):7350-7360. doi: 10.1002/alz.14166. Epub 2024 Sep 11.

PMID: 39258539 Free PMC article. Review. 

24. 

Associations of cerebrovascular disease and Alzheimer's disease pathology with cognitive decline: Analysis of the National Alzheimer's Coordinating Center Uniform Data Set. 

Chatterjee A, Lee S, Diaz V, Saloner R, Sanderson-Cimino M, deCarli C, Maillard P, Hinman J, Vossel K, Casaletto KB, Staffaroni AM, Paolillo EW, Kramer JH.

Neurobiol Aging. 2024 Oct;142:1-7. doi: 10.1016/j.neurobiolaging.2024.06.002. Epub 2024 Jun 21.

PMID: 39024720 Free PMC article. 

25. 

Leptin bioavailability and markers of brain atrophy and vascular injury in the middle age. 

Charisis S, Short MI, Bernal R, Kautz TF, Treviño HA, Mathews J, Dediós AGV, Muhammad JAS, Luckey AM, Aslam A, Himali JJ, Shipp EL, Habes M, Beiser AS, DeCarli C, Scarmeas N, Ramachandran VS, Seshadri S, Maillard P, Satizabal CL.

Alzheimers Dement. 2024 Sep;20(9):5849-5860. doi: 10.1002/alz.13879. Epub 2024 Aug 12.

PMID: 39132759 Free PMC article. 

26. 

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries. 

García-Marín LM, Campos AI, Diaz-Torres S, Rabinowitz JA, Ceja Z, Mitchell BL, Grasby KL, Thorp JG, Agartz I, Alhusaini S, Ames D, Amouyel P, Andreassen OA, Arfanakis K, Vasquez AA, Armstrong NJ, Athanasiu L, Bastin ME, Beiser AS, Bennett DA, Bis JC, Boks MP, Boomsma DI, Brodaty H, Brouwer RM, Buitelaar JK, Burkhardt R, Cahn W, Calhoun VD, Carmichael OT, Chakravarty M, Chen Q, Ching CRK, Cichon S, Crespo-Facorro B, Crivello F, Dale AM, Smith GD, de Geus EJ, De Jager PL, de Zubicaray GI, Debette S, DeCarli C, Depondt C, Desrivières S, Djurovic S, Ehrlich S, Erk S, Espeseth T, Fernández G, Filippi I, Fisher SE, Fleischman DA, Fletcher E, Fornage M, Forstner AJ, Francks C, Franke B, Ge T, Goldman AL, Grabe HJ, Green RC, Grimm O, Groenewold NA, Gruber O, Gudnason V, Håberg AK, Haukvik UK, Heinz A, Hibar DP, Hilal S, Himali JJ, Ho BC, Hoehn DF, Hoekstra PJ, Hofer E, Hoffmann W, Holmes AJ, Homuth G, Hosten N, Ikram MK, Ipser JC, Jack CR Jr, Jahanshad N, Jönsson EG, Kahn RS, Kanai R, Klein M, Knol MJ, Launer LJ, Lawrie SM, Hellard SL, Lee PH, Lemaître H, Li S, Liewald DC, Lin H, Longstreth WT Jr, Lopez OL, Luciano M, Maillard P, Marquand AF, Martin NG, Martinot JL, Mather KA, Mattay VS, McMahon KL, Mecocci P, Melle I, Meyer-Lindenberg A, Mirza-Schreiber N, Milaneschi Y, Mosley TH, Mühleisen TW, Müller-Myhsok B, Muñoz Maniega S, Nauck M, Nho K, Niessen WJ, Nöthen MM, Nyquist PA, Oosterlaan J, Pandolfo M, Paus T, Pausova Z, Penninx BW, Pike GB, Psaty BM, Pütz B, Reppermund S, Rietschel MD, Risacher SL, Romanczuk-Seiferth N, Romero-Garcia R, Roshchupkin GV, Rotter JI, Sachdev PS, Sämann PG, Saremi A, Sargurupremraj M, Saykin AJ, Schmaal L, Schmidt H, Schmidt R, Schofield PR, Scholz M, Schumann G, Schwarz E, Shen L, Shin J, Sisodiya SM, Smith AV, Smoller JW, Soininen HS, Steen VM, Stein DJ, Stein JL, Thomopoulos SI, Toga AW, Tordesillas-Gutiérrez D, Trollor JN, Valdes-Hernandez MC, van 't Ent D, van Bokhoven H, van der Meer D, van der Wee NJ, Vázquez-Bourgon J, Veltman DJ, Vernooij MW, Villringer A, Vinke LN, Völzke H, Walter H, Wardlaw JM, Weinberger DR, Weiner MW, Wen W, Westlye LT, Westman E, White T, Witte AV, Wolf C, Yang J, Zwiers MP, Ikram MA, Seshadri S, Thompson PM, Satizabal CL, Medland SE, Rentería ME.

medRxiv [Preprint]. 2024 Aug 15:2024.08.13.24311922. doi: 10.1101/2024.08.13.24311922.

Update in: Nat Genet. 2024 Nov;56(11):2333-2344. doi: 10.1038/s41588-024-01951-z. 

PMID: 39371125 Free PMC article. Preprint. 

27. 

Cerebrovascular reactivity MRI as a biomarker for cerebral small vessel disease-related cognitive decline: Multi-site validation in the MarkVCID Consortium. 

Liu P, Lin Z, Hazel K, Pottanat G, Xu C, Jiang D, Pillai JJ, Lucke E, Bauer CE, Gold BT, Greenberg SM, Helmer KG, Jann K, Jicha G, Kramer J, Maillard P, Mulavelil RM, Rodriguez P, Satizabal CL, Schwab K, Seshadri S, Singh H, Velarde Dediós ÁG, Wang DJJ, Kalyani RR, Moghekar A, Rosenberg PB, Yasar S, Albert M, Lu H.

Alzheimers Dement. 2024 Aug;20(8):5281-5289. doi: 10.1002/alz.13888. Epub 2024 Jul 1.

PMID: 38951718 Free PMC article. 

28. 

Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function. 

Liu X, Barisano G, Shao X, Jann K, Ringman JM, Lu H, Arfanakis K, Caprihan A, DeCarli C, Gold BT, Maillard P, Satizabal CL, Fadaee E, Habes M, Stables L, Singh H, Fischl B, van der Kouwe A, Schwab K, Helmer KG, Greenberg SM, Wang DJJ; MarkVCID Consortium.

Aging Dis. 2024 Aug 1;15(4):1885-1898. doi: 10.14336/AD.2023.0321-2.

PMID: 37307817 Free PMC article. 

29. 

Neurocognitive profiles are associated with subsequent brain integrity in a sample of Hispanics/Latinos: Findings from the SOL-INCA-MRI study (HCHS/SOL). 

Sapkota S, Maillard P, Stickel AM, Tarraf W, Gonzalez KA, Ivanovic V, Morlett-Paredes A, Cai J, Isasi CR, Lipton RB, Daviglus M, Testai FD, Lamar M, Gallo LC, Talavera GA, Agudelo C, Ramos AR, González HM, DeCarli C.

Alzheimers Dement (Amst). 2024 Jul 17;16(3):e12622. doi: 10.1002/dad2.12622. eCollection 2024 Jul-Sep.

PMID: 39021586 Free PMC article. 

30. 

MRI free water mediates the association between water exchange rate across the blood brain barrier and executive function among older adults. 

Pappas C, Bauer CE, Zachariou V, Maillard P, Caprihan A, Shao X, Wang DJJ, Gold BT.

Imaging Neurosci (Camb). 2024 Jun 5;2:1-15. doi: 10.1162/imag_a_00183. eCollection 2024 Jun 5.

PMID: 38947942 Free PMC article. 

31. 

Trends in Intracranial and Cerebral Volumes of Framingham Heart Study Participants Born 1930 to 1970. 

DeCarli C, Maillard P, Pase MP, Beiser AS, Kojis D, Satizabal CL, Himali JJ, Aparicio HJ, Fletcher E, Seshadri S.

JAMA Neurol. 2024 May 1;81(5):471-480. doi: 10.1001/jamaneurol.2024.0469.

PMID: 38526486 Free PMC article. 

32. 

Association of Blood Pressure With Brain White Matter Microstructural Integrity Assessed With MRI Diffusion Tensor Imaging in Healthy Young Adults. 

Won J, Maillard P, Shan K, Ashley J, Cardim D, Zhu DC, Zhang R.

Hypertension. 2024 May;81(5):1145-1155. doi: 10.1161/HYPERTENSIONAHA.123.22337. Epub 2024 Mar 15.

PMID: 38487873 Free PMC article. 

33. 

Enhancing Cognitive Performance Prediction through White Matter Hyperintensity Connectivity Assessment: A Multicenter Lesion Network Mapping Analysis of 3,485 Memory Clinic Patients. 

Petersen M, Coenen M, DeCarli C, De Luca A, van der Lelij E; Alzheimer’s Disease Neuroimaging Initiative; Barkhof F, Benke T, Chen CPLH, Dal-Bianco P, Dewenter A, Duering M, Enzinger C, Ewers M, Exalto LG, Fletcher EF, Franzmeier N, Hilal S, Hofer E, Koek HL, Maier AB, Maillard PM, McCreary CR, Papma JM, Pijnenburg YAL, Schmidt R, Smith EE, Steketee RME, van den Berg E, van der Flier WM, Venkatraghavan V, Venketasubramanian N, Vernooij MW, Wolters FJ, Xu X, Horn A, Patil KR, Eickhoff SB, Thomalla G, Biesbroek JM, Biessels GJ, Cheng B.

medRxiv [Preprint]. 2024 Apr 11:2024.03.28.24305007. doi: 10.1101/2024.03.28.24305007.

PMID: 38586023 Free PMC article. Preprint. 

34. 

Amyloid pathology and vascular risk are associated with distinct patterns of cerebral white matter hyperintensities: A multicenter study in 3132 memory clinic patients. 

Biesbroek JM, Coenen M, DeCarli C, Fletcher EM, Maillard PM; Alzheimer's Disease Neuroimaging Initiative; Barkhof F, Barnes J, Benke T, Chen CPLH, Dal-Bianco P, Dewenter A, Duering M, Enzinger C, Ewers M, Exalto LG, Franzmeier N, Hilal S, Hofer E, Koek HL, Maier AB, McCreary CR, Papma JM, Paterson RW, Pijnenburg YAL, Rubinski A, Schmidt R, Schott JM, Slattery CF, Smith EE, Sudre CH, Steketee RME, Teunissen CE, van den Berg E, van der Flier WM, Venketasubramanian N, Venkatraghavan V, Vernooij MW, Wolters FJ, Xin X, Kuijf HJ, Biessels GJ.

Alzheimers Dement. 2024 Apr;20(4):2980-2989. doi: 10.1002/alz.13765. Epub 2024 Mar 13.

PMID: 38477469 Free PMC article. 

35. 

Hypertension Trends and White Matter Brain Injury in the Offspring Framingham Heart Study Cohort. 

Petrea RE, Pinheiro A, Demissie S, Ekenze O, Aparicio HJ, Satizabal CL, Maillard P, DeCarli C, Beiser AS, Seshadri S, Lioutas VA, Rafael Romero J.

Hypertension. 2024 Jan;81(1):87-95. doi: 10.1161/HYPERTENSIONAHA.123.21264. Epub 2023 Oct 19.

PMID: 37855140 Free PMC article. 

36. 

Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease. 

Shirzadi Z, Schultz SA, Yau WW, Joseph-Mathurin N, Fitzpatrick CD, Levin R, Kantarci K, Preboske GM, Jack CR Jr, Farlow MR, Hassenstab J, Jucker M, Morris JC, Xiong C, Karch CM, Levey AI, Gordon BA, Schofield PR, Salloway SP, Perrin RJ, McDade E, Levin J, Cruchaga C, Allegri RF, Fox NC, Goate A, Day GS, Koeppe R, Chui HC, Berman S, Mori H, Sanchez-Valle R, Lee JH, Rosa-Neto P, Ruthirakuhan M, Wu CY, Swardfager W, Benzinger TLS, Sohrabi HR, Martins RN, Bateman RJ, Johnson KA, Sperling RA, Greenberg SM, Schultz AP, Chhatwal JP; Dominantly Inherited Alzheimer Network and the Alzheimer’s Disease Neuroimaging Initiative.

JAMA Neurol. 2023 Dec 1;80(12):1353-1363. doi: 10.1001/jamaneurol.2023.3618.

PMID: 37843849 Free PMC article. 

37. 

MISPEL: A supervised deep learning harmonization method for multi-scanner neuroimaging data. 

Torbati ME, Minhas DS, Laymon CM, Maillard P, Wilson JD, Chen CL, Crainiceanu CM, DeCarli CS, Hwang SJ, Tudorascu DL.

Med Image Anal. 2023 Oct;89:102926. doi: 10.1016/j.media.2023.102926. Epub 2023 Aug 9.

PMID: 37595405 Free PMC article. 

38. 

Relation of MRI-Visible Perivascular Spaces and Other MRI Markers of Cerebral Small Vessel Disease. 

Rodriguez Lara F, Toro AR, Pinheiro A, Demissie S, Ekenze O, Martinez O, Parva P, Charidimou A, Ghosh S, DeCarli C, Seshadri S, Habes M, Maillard P, Romero JR.

Brain Sci. 2023 Sep 14;13(9):1323. doi: 10.3390/brainsci13091323.

PMID: 37759924 Free PMC article. 

39. 

Placental growth factor as a sensitive biomarker for vascular cognitive impairment. 

Hinman JD, Elahi F, Chong D, Radabaugh H, Ferguson A, Maillard P, Thompson JF, Rosenberg GA, Sagare A, Moghekar A, Lu H, Lee T, Wilcock D, Satizabal CL, Tracy R, Seshadri S, Schwab K, Helmer K, Singh H, Kivisäkk P, Greenberg S, DeCarli C, Kramer J.

Alzheimers Dement. 2023 Aug;19(8):3519-3527. doi: 10.1002/alz.12974. Epub 2023 Feb 23.

PMID: 36815663 Free PMC article. 

40. 

Sexually dimorphic differences in angiogenesis markers predict brain aging trajectories. 

Torres-Espin A, Rabadaugh H, Fitzsimons S, Harvey D, Chou A, Lindberg C, Casaletto KB, Goldberger L, Staffaroni AM, Maillard P, Miller BL, DeCarli C, Hinman JD, Ferguson AR, Kramer JH, Elahi FM.

bioRxiv [Preprint]. 2023 Jul 18:2023.07.16.549192. doi: 10.1101/2023.07.16.549192.

Update in: Sci Transl Med. 2024 Nov 27;16(775):eadk3118. doi: 10.1126/scitranslmed.adk3118. 

PMID: 37503183 Free PMC article. Preprint. 

41. 

Neuroimaging standards for research into small vessel disease-advances since 2013. 

Duering M, Biessels GJ, Brodtmann A, Chen C, Cordonnier C, de Leeuw FE, Debette S, Frayne R, Jouvent E, Rost NS, Ter Telgte A, Al-Shahi Salman R, Backes WH, Bae HJ, Brown R, Chabriat H, De Luca A, deCarli C, Dewenter A, Doubal FN, Ewers M, Field TS, Ganesh A, Greenberg S, Helmer KG, Hilal S, Jochems ACC, Jokinen H, Kuijf H, Lam BYK, Lebenberg J, MacIntosh BJ, Maillard P, Mok VCT, Pantoni L, Rudilosso S, Satizabal CL, Schirmer MD, Schmidt R, Smith C, Staals J, Thrippleton MJ, van Veluw SJ, Vemuri P, Wang Y, Werring D, Zedde M, Akinyemi RO, Del Brutto OH, Markus HS, Zhu YC, Smith EE, Dichgans M, Wardlaw JM.

Lancet Neurol. 2023 Jul;22(7):602-618. doi: 10.1016/S1474-4422(23)00131-X. Epub 2023 May 23.

PMID: 37236211 Review. 

42. 

Association Between False Memories and Delusions in Alzheimer Disease. 

McLachlan E, Ocal D, Burgess N, Reeves S, Howard R; Alzheimer’s Disease Neuroimaging Initiative.

JAMA Psychiatry. 2023 Jul 1;80(7):700-709. doi: 10.1001/jamapsychiatry.2023.1012.

PMID: 37223934 Free PMC article. 

43. 

Strategic white matter hyperintensity locations for cognitive impairment: A multicenter lesion-symptom mapping study in 3525 memory clinic patients. 

Coenen M, Kuijf HJ, Huenges Wajer IMC, Duering M, Wolters FJ, Fletcher EF, Maillard PM; Alzheimer's Disease Neuroimaging Initiative; Barkhof F, Barnes J, Benke T, Boomsma JMF, Chen CPLH, Dal-Bianco P, Dewenter A, Enzinger C, Ewers M, Exalto LG, Franzmeier N, Groeneveld O, Hilal S, Hofer E, Koek DL, Maier AB, McCreary CR, Padilla CS, Papma JM, Paterson RW, Pijnenburg YAL, Rubinski A, Schmidt R, Schott JM, Slattery CF, Smith EE, Steketee RME, Sudre CH, van den Berg E, van der Flier WM, Venketasubramanian N, Vernooij MW, Xin X, DeCarli C, Biessels GJ, Biesbroek JM.

Alzheimers Dement. 2023 Jun;19(6):2420-2432. doi: 10.1002/alz.12827. Epub 2022 Dec 12.

PMID: 36504357 

44. 

Association of Early Adulthood Hypertension and Blood Pressure Change With Late-Life Neuroimaging Biomarkers. 

George KM, Maillard P, Gilsanz P, Fletcher E, Peterson RL, Fong J, Mayeda ER, Mungas DM, Barnes LL, Glymour MM, DeCarli C, Whitmer RA.

JAMA Netw Open. 2023 Apr 3;6(4):e236431. doi: 10.1001/jamanetworkopen.2023.6431.

PMID: 37010868 Free PMC article. 

45. 

Secular Trends in Head Size and Cerebral Volumes In the Framingham Heart Study for Birth Years 1902-1985. 

DeCarli C, Pase M, Beiser A, Kojis D, Satizabal C, Himali J, Aparicio H, Flether E, Maillard P, Seshadri S.

Res Sq [Preprint]. 2023 Jan 30:rs.3.rs-2524684. doi: 10.21203/rs.3.rs-2524684/v1.

PMID: 36778357 Free PMC article. Preprint. 

46. 

Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive Individuals. 

Öhrfelt A, Benedet AL, Ashton NJ, Kvartsberg H, Vandijck M, Weiner MW, Trojanowski JQ, Shaw LM, Zetterberg H, Blennow K; Alzheimer's Disease Neuroimaging Initiative.

Neurology. 2023 Jan 17;100(3):e275-e285. doi: 10.1212/WNL.0000000000201417. Epub 2022 Oct 3.

PMID: 36192174 Free PMC article. 

47. 

Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts. 

Coenen M, Biessels GJ, DeCarli C, Fletcher EF, Maillard PM; Alzheimer's Disease Neuroimaging Initiative; Barkhof F, Barnes J, Benke T, Boomsma JMF, P L H Chen C, Dal-Bianco P, Dewenter A, Duering M, Enzinger C, Ewers M, Exalto LG, Franzmeier N, Groeneveld O, Hilal S, Hofer E, Koek HL, Maier AB, McCreary CR, Papma JM, Paterson RW, Pijnenburg YAL, Rubinski A, Schmidt R, Schott JM, Slattery CF, Smith EE, Sudre CH, Steketee RME, van den Berg E, van der Flier WM, Venketasubramanian N, Vernooij MW, Wolters FJ, Xin X, Biesbroek JM, Kuijf HJ.

Neuroimage Clin. 2023;40:103547. doi: 10.1016/j.nicl.2023.103547. Epub 2023 Nov 23.

PMID: 38035457 Free PMC article. 

48. 

Multi-Site Cross-Site Inter-Rater and Test-Retest Reliability and Construct Validity of the MarkVCID White Matter Hyperintensity Growth and Regression Protocol. 

Bahrani AA, Abner EL, DeCarli CS, Barber JM, Sutton AC, Maillard P, Sandoval F, Arfanakis K, Yang YC, Evia AM, Schneider JA, Habes M, Franklin CG, Seshadri S, Satizabal CL, Caprihan A, Thompson JF, Rosenberg GA, Wang DJJ, Jann K, Zhao C, Lu H, Rosenberg PB, Albert MS, Ali DG, Singh H, Schwab K, Greenberg SM, Helmer KG, Powel DK, Gold BT, Goldstein LB, Wilcock DM, Jicha GA.

J Alzheimers Dis. 2023;96(2):683-693. doi: 10.3233/JAD-230629.

PMID: 37840499 Free PMC article. 

49. 

Association of Physical Inactivity with MRI Markers of Brain Aging: Assessing Mediation by Cardiometabolic and Epigenetic Factors. 

Spartano NL, Wang R, Yang Q, Chernofsky A, Murabito JM, Levy D, Vasan RS, DeCarli C, Maillard P, Seshadri S, Beiser AS.

J Alzheimers Dis. 2023;95(2):561-572. doi: 10.3233/JAD-230289.

PMID: 37574733 Free PMC article. 

50. 

White Matter Hyperintensity Volume and Amyloid-PET Synergistically Impact Memory Independent of Tau-PET in Older Adults Without Dementia. 

Edwards L, Thomas KR, Weigand AJ, Edmonds EC, Clark AL, Walker KS, Brenner EK, Nation DA, Maillard P, Bondi MW, Bangen KJ; Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2023;94(2):695-707. doi: 10.3233/JAD-221209.

PMID: 37302031 Free PMC article. 

51. 

MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium. 

Maillard P, Hillmer LJ, Lu H, Arfanakis K, Gold BT, Bauer CE, Kramer JH, Staffaroni AM, Stables L, Wang DJJ, Seshadri S, Satizabal CL, Beiser A, Habes M, Fornage M, Mosley TH, Rosenberg GA, Singh B, Singh H, Schwab K, Helmer KG, Greenberg SM, DeCarli C, Caprihan A.

Alzheimers Dement (Amst). 2022 Dec 13;14(1):e12362. doi: 10.1002/dad2.12362. eCollection 2022.

PMID: 36523847 Free PMC article. 

52. 

Association of Red Blood Cell Omega-3 Fatty Acids With MRI Markers and Cognitive Function in Midlife: The Framingham Heart Study. 

Satizabal CL, Himali JJ, Beiser AS, Ramachandran V, Melo van Lent D, Himali D, Aparicio HJ, Maillard P, DeCarli CS, Harris WS, Seshadri S.

Neurology. 2022 Dec 5;99(23):e2572-e2582. doi: 10.1212/WNL.0000000000201296.

PMID: 36198518 Free PMC article. 

53. 

Spatiotemporal Control of Vascular Ca_V1.2 by α1_C S1928 Phosphorylation. 

Martín-Aragón Baudel M, Flores-Tamez VA, Hong J, Reddy GR, Maillard P, Burns AE, Man KNM, Sasse KC, Ward SM, Catterall WA, Bers DM, Hell JW, Nieves-Cintrón M, Navedo MF.

Circ Res. 2022 Dec 2;131(12):1018-1033. doi: 10.1161/CIRCRESAHA.122.321479. Epub 2022 Nov 8.

PMID: 36345826 Free PMC article. 

54. 

Relations of postural change in blood pressure with hypertension-mediated organ damage in middle-aged adults of the Framingham heart study: A cross-sectional study. 

Cooper LL, Rong J, Maillard P, Beiser A, Hamburg NM, Larson MG, DeCarli C, Vasan RS, Seshadri S, Mitchell GF.

Front Cardiovasc Med. 2022 Nov 1;9:1013876. doi: 10.3389/fcvm.2022.1013876. eCollection 2022.

PMID: 36386360 Free PMC article. 

55. 

Multi-compartment diffusion magnetic resonance imaging models link tract-related characteristics with working memory performance in healthy older adults. 

Bauer CE, Zachariou V, Maillard P, Caprihan A, Gold BT.

Front Aging Neurosci. 2022 Oct 5;14:995425. doi: 10.3389/fnagi.2022.995425. eCollection 2022.

PMID: 36275003 Free PMC article. 

56. 

Plasma biomarkers predict cognitive trajectories in an ethnoracially and clinically diverse cohort: Mediation with hippocampal volume. 

Sapkota S, Erickson K, Harvey D, Tomaszewski-Farias SE, Olichney JM, Johnson DK, Dugger BN, Mungas DM, Fletcher E, Maillard P, Seshadri S, Satizabal CL, Kautz T, Parent D, Tracy RP, Maezawa I, Jin LW, DeCarli C.

Alzheimers Dement (Amst). 2022 Sep 1;14(1):e12349. doi: 10.1002/dad2.12349. eCollection 2022.

PMID: 36092690 Free PMC article. 

57. 

New insights into the genetic etiology of Alzheimer's disease and related dementias. 

Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, Kuulasmaa T, Yang Q, de Rojas I, Bis JC, Yaqub A, Prokic I, Chapuis J, Ahmad S, Giedraitis V, Aarsland D, Garcia-Gonzalez P, Abdelnour C, Alarcón-Martín E, Alcolea D, Alegret M, Alvarez I, Álvarez V, Armstrong NJ, Tsolaki A, Antúnez C, Appollonio I, Arcaro M, Archetti S, Pastor AA, Arosio B, Athanasiu L, Bailly H, Banaj N, Baquero M, Barral S, Beiser A, Pastor AB, Below JE, Benchek P, Benussi L, Berr C, Besse C, Bessi V, Binetti G, Bizarro A, Blesa R, Boada M, Boerwinkle E, Borroni B, Boschi S, Bossù P, Bråthen G, Bressler J, Bresner C, Brodaty H, Brookes KJ, Brusco LI, Buiza-Rueda D, Bûrger K, Burholt V, Bush WS, Calero M, Cantwell LB, Chene G, Chung J, Cuccaro ML, Carracedo Á, Cecchetti R, Cervera-Carles L, Charbonnier C, Chen HH, Chillotti C, Ciccone S, Claassen JAHR, Clark C, Conti E, Corma-Gómez A, Costantini E, Custodero C, Daian D, Dalmasso MC, Daniele A, Dardiotis E, Dartigues JF, de Deyn PP, de Paiva Lopes K, de Witte LD, Debette S, Deckert J, Del Ser T, Denning N, DeStefano A, Dichgans M, Diehl-Schmid J, Diez-Fairen M, Rossi PD, Djurovic S, Duron E, Düzel E, Dufouil C, Eiriksdottir G, Engelborghs S, Escott-Price V, Espinosa A, Ewers M, Faber KM, Fabrizio T, Nielsen SF, Fardo DW, Farotti L, Fenoglio C, Fernández-Fuertes M, Ferrari R, Ferreira CB, Ferri E, Fin B, Fischer P, Fladby T, Fließbach K, Fongang B, Fornage M, Fortea J, Foroud TM, Fostinelli S, Fox NC, Franco-Macías E, Bullido MJ, Frank-García A, Froelich L, Fulton-Howard B, Galimberti D, García-Alberca JM, García-González P, Garcia-Madrona S, Garcia-Ribas G, Ghidoni R, Giegling I, Giorgio G, Goate AM, Goldhardt O, Gomez-Fonseca D, González-Pérez A, Graff C, Grande G, Green E, Grimmer T, Grünblatt E, Grunin M, Gudnason V, Guetta-Baranes T, Haapasalo A, Hadjigeorgiou G, Haines JL, Hamilton-Nelson KL, Hampel H, Hanon O, Hardy J, Hartmann AM, Hausner L, Harwood J, Heilmann-Heimbach S, Helisalmi S, Heneka MT, Hernández I, Herrmann MJ, Hoffmann P, Holmes C, Holstege H, Vilas RH, Hulsman M, Humphrey J, Biessels GJ, Jian X, Johansson C, Jun GR, Kastumata Y, Kauwe J, Kehoe PG, Kilander L, Ståhlbom AK, Kivipelto M, Koivisto A, Kornhuber J, Kosmidis MH, Kukull WA, Kuksa PP, Kunkle BW, Kuzma AB, Lage C, Laukka EJ, Launer L, Lauria A, Lee CY, Lehtisalo J, Lerch O, Lleó A, Longstreth W Jr, Lopez O, de Munain AL, Love S, Löwemark M, Luckcuck L, Lunetta KL, Ma Y, Macías J, MacLeod CA, Maier W, Mangialasche F, Spallazzi M, Marquié M, Marshall R, Martin ER, Montes AM, Rodríguez CM, Masullo C, Mayeux R, Mead S, Mecocci P, Medina M, Meggy A, Mehrabian S, Mendoza S, Menéndez-González M, Mir P, Moebus S, Mol M, Molina-Porcel L, Montrreal L, Morelli L, Moreno F, Morgan K, Mosley T, Nöthen MM, Muchnik C, Mukherjee S, Nacmias B, Ngandu T, Nicolas G, Nordestgaard BG, Olaso R, Orellana A, Orsini M, Ortega G, Padovani A, Paolo C, Papenberg G, Parnetti L, Pasquier F, Pastor P, Peloso G, Pérez-Cordón A, Pérez-Tur J, Pericard P, Peters O, Pijnenburg YAL, Pineda JA, Piñol-Ripoll G, Pisanu C, Polak T, Popp J, Posthuma D, Priller J, Puerta R, Quenez O, Quintela I, Thomassen JQ, Rábano A, Rainero I, Rajabli F, Ramakers I, Real LM, Reinders MJT, Reitz C, Reyes-Dumeyer D, Ridge P, Riedel-Heller S, Riederer P, Roberto N, Rodriguez-Rodriguez E, Rongve A, Allende IR, Rosende-Roca M, Royo JL, Rubino E, Rujescu D, Sáez ME, Sakka P, Saltvedt I, Sanabria Á, Sánchez-Arjona MB, Sanchez-Garcia F, Juan PS, Sánchez-Valle R, Sando SB, Sarnowski C, Satizabal CL, Scamosci M, Scarmeas N, Scarpini E, Scheltens P, Scherbaum N, Scherer M, Schmid M, Schneider A, Schott JM, Selbæk G, Seripa D, Serrano M, Sha J, Shadrin AA, Skrobot O, Slifer S, Snijders GJL, Soininen H, Solfrizzi V, Solomon A, Song Y, Sorbi S, Sotolongo-Grau O, Spalletta G, Spottke A, Squassina A, Stordal E, Tartan JP, Tárraga L, Tesí N, Thalamuthu A, Thomas T, Tosto G, Traykov L, Tremolizzo L, Tybjærg-Hansen A, Uitterlinden A, Ullgren A, Ulstein I, Valero S, Valladares O, Broeckhoven CV, Vance J, Vardarajan BN, van der Lugt A, Dongen JV, van Rooij J, van Swieten J, Vandenberghe R, Verhey F, Vidal JS, Vogelgsang J, Vyhnalek M, Wagner M, Wallon D, Wang LS, Wang R, Weinhold L, Wiltfang J, Windle G, Woods B, Yannakoulia M, Zare H, Zhao Y, Zhang X, Zhu C, Zulaica M; EADB; GR@ACE; DEGESCO; EADI; GERAD; Demgene; FinnGen; ADGC; CHARGE; Farrer LA, Psaty BM, Ghanbari M, Raj T, Sachdev P, Mather K, Jessen F, Ikram MA, de Mendonça A, Hort J, Tsolaki M, Pericak-Vance MA, Amouyel P, Williams J, Frikke-Schmidt R, Clarimon J, Deleuze JF, Rossi G, Seshadri S, Andreassen OA, Ingelsson M, Hiltunen M, Sleegers K, Schellenberg GD, van Duijn CM, Sims R, van der Flier WM, Ruiz A, Ramirez A, Lambert JC.

Nat Genet. 2022 Apr;54(4):412-436. doi: 10.1038/s41588-022-01024-z. Epub 2022 Apr 4.

PMID: 35379992 Free PMC article. 

58. 

Instrumental validation of free water, peak-width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits. 

Maillard P, Lu H, Arfanakis K, Gold BT, Bauer CE, Zachariou V, Stables L, Wang DJJ, Jann K, Seshadri S, Duering M, Hillmer LJ, Rosenberg GA, Snoussi H, Sepehrband F, Habes M, Singh B, Kramer JH, Corriveau RA, Singh H, Schwab K, Helmer KG, Greenberg SM, Caprihan A, DeCarli C, Satizabal CL; MarkVCID Consortium.

Alzheimers Dement (Amst). 2022 Mar 28;14(1):e12261. doi: 10.1002/dad2.12261. eCollection 2022.

PMID: 35382232 Free PMC article. 

59. 

Relations of Metabolic Health and Obesity to Brain Aging in Young to Middle-Aged Adults. 

Angoff R, Himali JJ, Maillard P, Aparicio HJ, Vasan RS, Seshadri S, Beiser AS, Tsao CW.

J Am Heart Assoc. 2022 Mar 15;11(6):e022107. doi: 10.1161/JAHA.121.022107. Epub 2022 Mar 1.

PMID: 35229662 Free PMC article. 

60. 

Author Correction: Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans. 

Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ.

Sci Rep. 2022 Feb 1;12(1):2008. doi: 10.1038/s41598-022-05977-3.

PMID: 35105918 Free PMC article. No abstract available. 

61. 

Multi-scanner Harmonization of Paired Neuroimaging Data via Structure Preserving Embedding Learning. 

Torbati ME, Tudorascu DL, Minhas DS, Maillard P, DeCarli CS, Hwang SJ.

IEEE Int Conf Comput Vis Workshops. 2021 Oct;2021:3277-3286. doi: 10.1109/ICCVW54120.2021.00367. Epub 2021 Nov 24.

PMID: 34909551 Free PMC article. 

62. 

Elevated complement mediator levels in endothelial-derived plasma exosomes implicate endothelial innate inflammation in diminished brain function of aging humans. 

Elahi FM, Harvey D, Altendahl M, Brathaban N, Fernandes N, Casaletto KB, Staffaroni AM, Maillard P, Hinman JD, Miller BL, DeCarli C, Kramer JH, Goetzl EJ.

Sci Rep. 2021 Aug 10;11(1):16198. doi: 10.1038/s41598-021-91759-2.

PMID: 34376699 Free PMC article. 

63. 

Coronary Artery Calcium Assessed Years Before Was Positively Associated With Subtle White Matter Injury of the Brain in Asymptomatic Middle-Aged Men: The Framingham Heart Study. 

Suzuki H, Davis-Plourde K, Beiser A, Kunimura A, Miura K, DeCarli C, Maillard P, Mitchell GF, Vasan RS, Seshadri S, Fujiyoshi A.

Circ Cardiovasc Imaging. 2021 Jul;14(7):e011753. doi: 10.1161/CIRCIMAGING.120.011753. Epub 2021 Jul 14.

PMID: 34256573 Free PMC article. 

64. 

MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols. 

Lu H, Kashani AH, Arfanakis K, Caprihan A, DeCarli C, Gold BT, Li Y, Maillard P, Satizabal CL, Stables L, Wang DJJ, Corriveau RA, Singh H, Smith EE, Fischl B, van der Kouwe A, Schwab K, Helmer KG, Greenberg SM; MarkVCID Consortium.

Alzheimers Dement. 2021 Apr;17(4):716-725. doi: 10.1002/alz.12216. Epub 2021 Jan 21.

PMID: 33480157 Free PMC article. 

65. 

Slow-Wave Sleep and MRI Markers of Brain Aging in a Community-Based Sample. 

Baril AA, Beiser AS, Mysliwiec V, Sanchez E, DeCarli CS, Redline S, Gottlieb DJ, Maillard P, Romero JR, Satizabal CL, Zucker JM, Seshadri S, Pase MP, Himali JJ.

Neurology. 2021 Mar 9;96(10):e1462-e1469. doi: 10.1212/WNL.0000000000011377. Epub 2020 Dec 22.

PMID: 33361258 Free PMC article. 

66. 

Digital sleep measures and white matter health in the Framingham Heart Study. 

Thomas RJ, Kim H, Maillard P, DeCarli CS, Heckman EJ, Karjadi C, Ang TFA, Au R.

Explor Med. 2021;2(3):253-267. doi: 10.37349/emed.2021.00045. Epub 2021 Jun 30.

PMID: 34927164 Free PMC article. 

67. 

Association of vascular brain injury, neurodegeneration, amyloid, and cognitive trajectory. 

Han JW, Maillard P, Harvey D, Fletcher E, Martinez O, Johnson DK, Olichney JM, Farias ST, Villeneuve S, Jagust W, Mungas D, DeCarli C.

Neurology. 2020 Nov 10;95(19):e2622-e2634. doi: 10.1212/WNL.0000000000010531. Epub 2020 Jul 30.

PMID: 32732300 Free PMC article. 

68. 

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults. 

Hofer E, Roshchupkin GV, Adams HHH, Knol MJ, Lin H, Li S, Zare H, Ahmad S, Armstrong NJ, Satizabal CL, Bernard M, Bis JC, Gillespie NA, Luciano M, Mishra A, Scholz M, Teumer A, Xia R, Jian X, Mosley TH, Saba Y, Pirpamer L, Seiler S, Becker JT, Carmichael O, Rotter JI, Psaty BM, Lopez OL, Amin N, van der Lee SJ, Yang Q, Himali JJ, Maillard P, Beiser AS, DeCarli C, Karama S, Lewis L, Harris M, Bastin ME, Deary IJ, Veronica Witte A, Beyer F, Loeffler M, Mather KA, Schofield PR, Thalamuthu A, Kwok JB, Wright MJ, Ames D, Trollor J, Jiang J, Brodaty H, Wen W, Vernooij MW, Hofman A, Uitterlinden AG, Niessen WJ, Wittfeld K, Bülow R, Völker U, Pausova Z, Bruce Pike G, Maingault S, Crivello F, Tzourio C, Amouyel P, Mazoyer B, Neale MC, Franz CE, Lyons MJ, Panizzon MS, Andreassen OA, Dale AM, Logue M, Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Stein JL, Thompson PM, Medland SE; ENIGMA consortium; Sachdev PS, Kremen WS, Wardlaw JM, Villringer A, van Duijn CM, Grabe HJ, Longstreth WT Jr, Fornage M, Paus T, Debette S, Ikram MA, Schmidt H, Schmidt R, Seshadri S.

Nat Commun. 2020 Sep 22;11(1):4796. doi: 10.1038/s41467-020-18367-y.

PMID: 32963231 Free PMC article. 

69. 

Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities. 

Armstrong NJ, Mather KA, Sargurupremraj M, Knol MJ, Malik R, Satizabal CL, Yanek LR, Wen W, Gudnason VG, Dueker ND, Elliott LT, Hofer E, Bis J, Jahanshad N, Li S, Logue MA, Luciano M, Scholz M, Smith AV, Trompet S, Vojinovic D, Xia R, Alfaro-Almagro F, Ames D, Amin N, Amouyel P, Beiser AS, Brodaty H, Deary IJ, Fennema-Notestine C, Gampawar PG, Gottesman R, Griffanti L, Jack CR Jr, Jenkinson M, Jiang J, Kral BG, Kwok JB, Lampe L, C M Liewald D, Maillard P, Marchini J, Bastin ME, Mazoyer B, Pirpamer L, Rafael Romero J, Roshchupkin GV, Schofield PR, Schroeter ML, Stott DJ, Thalamuthu A, Trollor J, Tzourio C, van der Grond J, Vernooij MW, Witte VA, Wright MJ, Yang Q, Morris Z, Siggurdsson S, Psaty B, Villringer A, Schmidt H, Haberg AK, van Duijn CM, Jukema JW, Dichgans M, Sacco RL, Wright CB, Kremen WS, Becker LC, Thompson PM, Mosley TH, Wardlaw JM, Ikram MA, Adams HHH, Seshadri S, Sachdev PS, Smith SM, Launer L, Longstreth W, DeCarli C, Schmidt R, Fornage M, Debette S, Nyquist PA.

Stroke. 2020 Jul;51(7):2111-2121. doi: 10.1161/STROKEAHA.119.027544. Epub 2020 Jun 10.

PMID: 32517579 Free PMC article. 

70. 

The genetic architecture of the human cerebral cortex. 

Grasby KL, Jahanshad N, Painter JN, Colodro-Conde L, Bralten J, Hibar DP, Lind PA, Pizzagalli F, Ching CRK, McMahon MAB, Shatokhina N, Zsembik LCP, Thomopoulos SI, Zhu AH, Strike LT, Agartz I, Alhusaini S, Almeida MAA, Alnæs D, Amlien IK, Andersson M, Ard T, Armstrong NJ, Ashley-Koch A, Atkins JR, Bernard M, Brouwer RM, Buimer EEL, Bülow R, Bürger C, Cannon DM, Chakravarty M, Chen Q, Cheung JW, Couvy-Duchesne B, Dale AM, Dalvie S, de Araujo TK, de Zubicaray GI, de Zwarte SMC, den Braber A, Doan NT, Dohm K, Ehrlich S, Engelbrecht HR, Erk S, Fan CC, Fedko IO, Foley SF, Ford JM, Fukunaga M, Garrett ME, Ge T, Giddaluru S, Goldman AL, Green MJ, Groenewold NA, Grotegerd D, Gurholt TP, Gutman BA, Hansell NK, Harris MA, Harrison MB, Haswell CC, Hauser M, Herms S, Heslenfeld DJ, Ho NF, Hoehn D, Hoffmann P, Holleran L, Hoogman M, Hottenga JJ, Ikeda M, Janowitz D, Jansen IE, Jia T, Jockwitz C, Kanai R, Karama S, Kasperaviciute D, Kaufmann T, Kelly S, Kikuchi M, Klein M, Knapp M, Knodt AR, Krämer B, Lam M, Lancaster TM, Lee PH, Lett TA, Lewis LB, Lopes-Cendes I, Luciano M, Macciardi F, Marquand AF, Mathias SR, Melzer TR, Milaneschi Y, Mirza-Schreiber N, Moreira JCV, Mühleisen TW, Müller-Myhsok B, Najt P, Nakahara S, Nho K, Olde Loohuis LM, Orfanos DP, Pearson JF, Pitcher TL, Pütz B, Quidé Y, Ragothaman A, Rashid FM, Reay WR, Redlich R, Reinbold CS, Repple J, Richard G, Riedel BC, Risacher SL, Rocha CS, Mota NR, Salminen L, Saremi A, Saykin AJ, Schlag F, Schmaal L, Schofield PR, Secolin R, Shapland CY, Shen L, Shin J, Shumskaya E, Sønderby IE, Sprooten E, Tansey KE, Teumer A, Thalamuthu A, Tordesillas-Gutiérrez D, Turner JA, Uhlmann A, Vallerga CL, van der Meer D, van Donkelaar MMJ, van Eijk L, van Erp TGM, van Haren NEM, van Rooij D, van Tol MJ, Veldink JH, Verhoef E, Walton E, Wang M, Wang Y, Wardlaw JM, Wen W, Westlye LT, Whelan CD, Witt SH, Wittfeld K, Wolf C, Wolfers T, Wu JQ, Yasuda CL, Zaremba D, Zhang Z, Zwiers MP, Artiges E, Assareh AA, Ayesa-Arriola R, Belger A, Brandt CL, Brown GG, Cichon S, Curran JE, Davies GE, Degenhardt F, Dennis MF, Dietsche B, Djurovic S, Doherty CP, Espiritu R, Garijo D, Gil Y, Gowland PA, Green RC, Häusler AN, Heindel W, Ho BC, Hoffmann WU, Holsboer F, Homuth G, Hosten N, Jack CR Jr, Jang M, Jansen A, Kimbrel NA, Kolskår K, Koops S, Krug A, Lim KO, Luykx JJ, Mathalon DH, Mather KA, Mattay VS, Matthews S, Mayoral Van Son J, McEwen SC, Melle I, Morris DW, Mueller BA, Nauck M, Nordvik JE, Nöthen MM, O'Leary DS, Opel N, Martinot MP, Pike GB, Preda A, Quinlan EB, Rasser PE, Ratnakar V, Reppermund S, Steen VM, Tooney PA, Torres FR, Veltman DJ, Voyvodic JT, Whelan R, White T, Yamamori H, Adams HHH, Bis JC, Debette S, Decarli C, Fornage M, Gudnason V, Hofer E, Ikram MA, Launer L, Longstreth WT, Lopez OL, Mazoyer B, Mosley TH, Roshchupkin GV, Satizabal CL, Schmidt R, Seshadri S, Yang Q; Alzheimer’s Disease Neuroimaging Initiative; CHARGE Consortium; EPIGEN Consortium; IMAGEN Consortium; SYS Consortium; Parkinson’s Progression Markers Initiative; Alvim MKM, Ames D, Anderson TJ, Andreassen OA, Arias-Vasquez A, Bastin ME, Baune BT, Beckham JC, Blangero J, Boomsma DI, Brodaty H, Brunner HG, Buckner RL, Buitelaar JK, Bustillo JR, Cahn W, Cairns MJ, Calhoun V, Carr VJ, Caseras X, Caspers S, Cavalleri GL, Cendes F, Corvin A, Crespo-Facorro B, Dalrymple-Alford JC, Dannlowski U, de Geus EJC, Deary IJ, Delanty N, Depondt C, Desrivières S, Donohoe G, Espeseth T, Fernández G, Fisher SE, Flor H, Forstner AJ, Francks C, Franke B, Glahn DC, Gollub RL, Grabe HJ, Gruber O, Håberg AK, Hariri AR, Hartman CA, Hashimoto R, Heinz A, Henskens FA, Hillegers MHJ, Hoekstra PJ, Holmes AJ, Hong LE, Hopkins WD, Hulshoff Pol HE, Jernigan TL, Jönsson EG, Kahn RS, Kennedy MA, Kircher TTJ, Kochunov P, Kwok JBJ, Le Hellard S, Loughland CM, Martin NG, Martinot JL, McDonald C, McMahon KL, Meyer-Lindenberg A, Michie PT, Morey RA, Mowry B, Nyberg L, Oosterlaan J, Ophoff RA, Pantelis C, Paus T, Pausova Z, Penninx BWJH, Polderman TJC, Posthuma D, Rietschel M, Roffman JL, Rowland LM, Sachdev PS, Sämann PG, Schall U, Schumann G, Scott RJ, Sim K, Sisodiya SM, Smoller JW, Sommer IE, St Pourcain B, Stein DJ, Toga AW, Trollor JN, Van der Wee NJA, van 't Ent D, Völzke H, Walter H, Weber B, Weinberger DR, Wright MJ, Zhou J, Stein JL, Thompson PM, Medland SE; Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)—Genetics working group.

Science. 2020 Mar 20;367(6484):eaay6690. doi: 10.1126/science.aay6690.

PMID: 32193296 Free PMC article. 

71. 

An IL-18-centered inflammatory network as a biomarker for cerebral white matter injury. 

Altendahl M, Maillard P, Harvey D, Cotter D, Walters S, Wolf A, Singh B, Kakarla V, Azizkhanian I, Sheth SA, Xiao G, Fox E, You M, Leng M, Elashoff D, Kramer JH, Decarli C, Elahi F, Hinman JD.

PLoS One. 2020 Jan 24;15(1):e0227835. doi: 10.1371/journal.pone.0227835. eCollection 2020.

PMID: 31978079 Free PMC article. 

72. 

Genetic architecture of subcortical brain structures in 38,851 individuals. 

Satizabal CL, Adams HHH, Hibar DP, White CC, Knol MJ, Stein JL, Scholz M, Sargurupremraj M, Jahanshad N, Roshchupkin GV, Smith AV, Bis JC, Jian X, Luciano M, Hofer E, Teumer A, van der Lee SJ, Yang J, Yanek LR, Lee TV, Li S, Hu Y, Koh JY, Eicher JD, Desrivières S, Arias-Vasquez A, Chauhan G, Athanasiu L, Rentería ME, Kim S, Hoehn D, Armstrong NJ, Chen Q, Holmes AJ, den Braber A, Kloszewska I, Andersson M, Espeseth T, Grimm O, Abramovic L, Alhusaini S, Milaneschi Y, Papmeyer M, Axelsson T, Ehrlich S, Roiz-Santiañez R, Kraemer B, Håberg AK, Jones HJ, Pike GB, Stein DJ, Stevens A, Bralten J, Vernooij MW, Harris TB, Filippi I, Witte AV, Guadalupe T, Wittfeld K, Mosley TH, Becker JT, Doan NT, Hagenaars SP, Saba Y, Cuellar-Partida G, Amin N, Hilal S, Nho K, Mirza-Schreiber N, Arfanakis K, Becker DM, Ames D, Goldman AL, Lee PH, Boomsma DI, Lovestone S, Giddaluru S, Le Hellard S, Mattheisen M, Bohlken MM, Kasperaviciute D, Schmaal L, Lawrie SM, Agartz I, Walton E, Tordesillas-Gutierrez D, Davies GE, Shin J, Ipser JC, Vinke LN, Hoogman M, Jia T, Burkhardt R, Klein M, Crivello F, Janowitz D, Carmichael O, Haukvik UK, Aribisala BS, Schmidt H, Strike LT, Cheng CY, Risacher SL, Pütz B, Fleischman DA, Assareh AA, Mattay VS, Buckner RL, Mecocci P, Dale AM, Cichon S, Boks MP, Matarin M, Penninx BWJH, Calhoun VD, Chakravarty MM, Marquand AF, Macare C, Kharabian Masouleh S, Oosterlaan J, Amouyel P, Hegenscheid K, Rotter JI, Schork AJ, Liewald DCM, de Zubicaray GI, Wong TY, Shen L, Sämann PG, Brodaty H, Roffman JL, de Geus EJC, Tsolaki M, Erk S, van Eijk KR, Cavalleri GL, van der Wee NJA, McIntosh AM, Gollub RL, Bulayeva KB, Bernard M, Richards JS, Himali JJ, Loeffler M, Rommelse N, Hoffmann W, Westlye LT, Valdés Hernández MC, Hansell NK, van Erp TGM, Wolf C, Kwok JBJ, Vellas B, Heinz A, Olde Loohuis LM, Delanty N, Ho BC, Ching CRK, Shumskaya E, Singh B, Hofman A, van der Meer D, Homuth G, Psaty BM, Bastin ME, Montgomery GW, Foroud TM, Reppermund S, Hottenga JJ, Simmons A, Meyer-Lindenberg A, Cahn W, Whelan CD, van Donkelaar MMJ, Yang Q, Hosten N, Green RC, Thalamuthu A, Mohnke S, Hulshoff Pol HE, Lin H, Jack CR Jr, Schofield PR, Mühleisen TW, Maillard P, Potkin SG, Wen W, Fletcher E, Toga AW, Gruber O, Huentelman M, Davey Smith G, Launer LJ, Nyberg L, Jönsson EG, Crespo-Facorro B, Koen N, Greve DN, Uitterlinden AG, Weinberger DR, Steen VM, Fedko IO, Groenewold NA, Niessen WJ, Toro R, Tzourio C, Longstreth WT Jr, Ikram MK, Smoller JW, van Tol MJ, Sussmann JE, Paus T, Lemaître H, Schroeter ML, Mazoyer B, Andreassen OA, Holsboer F, Depondt C, Veltman DJ, Turner JA, Pausova Z, Schumann G, van Rooij D, Djurovic S, Deary IJ, McMahon KL, Müller-Myhsok B, Brouwer RM, Soininen H, Pandolfo M, Wassink TH, Cheung JW, Wolfers T, Martinot JL, Zwiers MP, Nauck M, Melle I, Martin NG, Kanai R, Westman E, Kahn RS, Sisodiya SM, White T, Saremi A, van Bokhoven H, Brunner HG, Völzke H, Wright MJ, van 't Ent D, Nöthen MM, Ophoff RA, Buitelaar JK, Fernández G, Sachdev PS, Rietschel M, van Haren NEM, Fisher SE, Beiser AS, Francks C, Saykin AJ, Mather KA, Romanczuk-Seiferth N, Hartman CA, DeStefano AL, Heslenfeld DJ, Weiner MW, Walter H, Hoekstra PJ, Nyquist PA, Franke B, Bennett DA, Grabe HJ, Johnson AD, Chen C, van Duijn CM, Lopez OL, Fornage M, Wardlaw JM, Schmidt R, DeCarli C, De Jager PL, Villringer A, Debette S, Gudnason V, Medland SE, Shulman JM, Thompson PM, Seshadri S, Ikram MA.

Nat Genet. 2019 Nov;51(11):1624-1636. doi: 10.1038/s41588-019-0511-y. Epub 2019 Oct 21.

PMID: 31636452 Free PMC article. 

73. 

Plasma total-tau as a biomarker of stroke risk in the community. 

Pase MP, Himali JJ, Aparicio HJ, Romero JR, Satizabal CL, Maillard P, DeCarli C, Beiser AS, Seshadri S.

Ann Neurol. 2019 Sep;86(3):463-467. doi: 10.1002/ana.25542. Epub 2019 Jul 29.

PMID: 31271449 Free PMC article. 

74. 

White Matter Hyperintensities and Hippocampal Atrophy in Relation to Cognition: The 90+ Study. 

Legdeur N, Visser PJ, Woodworth DC, Muller M, Fletcher E, Maillard P, Scheltens P, DeCarli C, Kawas CH, Corrada MM.

J Am Geriatr Soc. 2019 Sep;67(9):1827-1834. doi: 10.1111/jgs.15990. Epub 2019 Jun 6.

PMID: 31169919 Free PMC article. 

75. 

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes. 

van der Lee SJ, Knol MJ, Chauhan G, Satizabal CL, Smith AV, Hofer E, Bis JC, Hibar DP, Hilal S, van den Akker EB, Arfanakis K, Bernard M, Yanek LR, Amin N, Crivello F, Cheung JW, Harris TB, Saba Y, Lopez OL, Li S, van der Grond J, Yu L, Paus T, Roshchupkin GV, Amouyel P, Jahanshad N, Taylor KD, Yang Q, Mathias RA, Boehringer S, Mazoyer B, Rice K, Cheng CY, Maillard P, van Heemst D, Wong TY, Niessen WJ, Beiser AS, Beekman M, Zhao W, Nyquist PA, Chen C, Launer LJ, Psaty BM, Ikram MK, Vernooij MW, Schmidt H, Pausova Z, Becker DM, De Jager PL, Thompson PM, van Duijn CM, Bennett DA, Slagboom PE, Schmidt R, Longstreth WT, Ikram MA, Seshadri S, Debette S, Gudnason V, Adams HHH, DeCarli C.

Commun Biol. 2019 Aug 2;2:285. doi: 10.1038/s42003-019-0537-9. eCollection 2019.

PMID: 31396565 Free PMC article. 

76. 

Cerebral white matter free water: A sensitive biomarker of cognition and function. 

Maillard P, Fletcher E, Singh B, Martinez O, Johnson DK, Olichney JM, Farias ST, DeCarli C.

Neurology. 2019 May 7;92(19):e2221-e2231. doi: 10.1212/WNL.0000000000007449. Epub 2019 Apr 5.

PMID: 30952798 Free PMC article. 

77. 

Association of Accelerometer-Measured Light-Intensity Physical Activity With Brain Volume: The Framingham Heart Study. 

Spartano NL, Davis-Plourde KL, Himali JJ, Andersson C, Pase MP, Maillard P, DeCarli C, Murabito JM, Beiser AS, Vasan RS, Seshadri S.

JAMA Netw Open. 2019 Apr 5;2(4):e192745. doi: 10.1001/jamanetworkopen.2019.2745.

PMID: 31002329 Free PMC article. 

78. 

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting. 

Chauhan G, Adams HHH, Satizabal CL, Bis JC, Teumer A, Sargurupremraj M, Hofer E, Trompet S, Hilal S, Smith AV, Jian X, Malik R, Traylor M, Pulit SL, Amouyel P, Mazoyer B, Zhu YC, Kaffashian S, Schilling S, Beecham GW, Montine TJ, Schellenberg GD, Kjartansson O, Guðnason V, Knopman DS, Griswold ME, Windham BG, Gottesman RF, Mosley TH, Schmidt R, Saba Y, Schmidt H, Takeuchi F, Yamaguchi S, Nabika T, Kato N, Rajan KB, Aggarwal NT, De Jager PL, Evans DA, Psaty BM, Rotter JI, Rice K, Lopez OL, Liao J, Chen C, Cheng CY, Wong TY, Ikram MK, van der Lee SJ, Amin N, Chouraki V, DeStefano AL, Aparicio HJ, Romero JR, Maillard P, DeCarli C, Wardlaw JM, Hernández MDCV, Luciano M, Liewald D, Deary IJ, Starr JM, Bastin ME, Muñoz Maniega S, Slagboom PE, Beekman M, Deelen J, Uh HW, Lemmens R, Brodaty H, Wright MJ, Ames D, Boncoraglio GB, Hopewell JC, Beecham AH, Blanton SH, Wright CB, Sacco RL, Wen W, Thalamuthu A, Armstrong NJ, Chong E, Schofield PR, Kwok JB, van der Grond J, Stott DJ, Ford I, Jukema JW, Vernooij MW, Hofman A, Uitterlinden AG, van der Lugt A, Wittfeld K, Grabe HJ, Hosten N, von Sarnowski B, Völker U, Levi C, Jimenez-Conde J, Sharma P, Sudlow CLM, Rosand J, Woo D, Cole JW, Meschia JF, Slowik A, Thijs V, Lindgren A, Melander O, Grewal RP, Rundek T, Rexrode K, Rothwell PM, Arnett DK, Jern C, Johnson JA, Benavente OR, Wasssertheil-Smoller S, Lee JM, Wong Q, Mitchell BD, Rich SS, McArdle PF, Geerlings MI, van der Graaf Y, de Bakker PIW, Asselbergs FW, Srikanth V, Thomson R, McWhirter R, Moran C, Callisaya M, Phan T, Rutten-Jacobs LCA, Bevan S, Tzourio C, Mather KA, Sachdev PS, van Duijn CM, Worrall BB, Dichgans M, Kittner SJ, Markus HS, Ikram MA, Fornage M, Launer LJ, Seshadri S, Longstreth WT Jr, Debette S; Stroke Genetics Network (SiGN), the International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer's Disease Genetics Consortium (ADGC), and the Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium.

Neurology. 2019 Jan 28;92(5):e486-e503. doi: 10.1212/WNL.0000000000006851.

PMID: 30651383 Free PMC article. 

79. 

Vascular Burden Score Impacts Cognition Independent of Amyloid PET and MRI Measures of Alzheimer's Disease and Vascular Brain Injury. 

DeCarli C, Villeneuve S, Maillard P, Harvey D, Singh B, Carmichael O, Fletcher E, Olichney J, Farias S, Jagust W, Reed B, Mungas D.

J Alzheimers Dis. 2019;68(1):187-196. doi: 10.3233/JAD-180965.

PMID: 30775991 Free PMC article. 

80. 

Cerebral tract integrity relates to white matter hyperintensities, cortex volume, and cognition. 

Seiler S, Fletcher E, Hassan-Ali K, Weinstein M, Beiser A, Himali JJ, Satizabal CL, Seshadri S, DeCarli C, Maillard P.

Neurobiol Aging. 2018 Dec;72:14-22. doi: 10.1016/j.neurobiolaging.2018.08.005. Epub 2018 Aug 9.

PMID: 30172922 Free PMC article. 

81. 

Circulating cortisol and cognitive and structural brain measures: The Framingham Heart Study. 

Echouffo-Tcheugui JB, Conner SC, Himali JJ, Maillard P, DeCarli CS, Beiser AS, Vasan RS, Seshadri S.

Neurology. 2018 Nov 20;91(21):e1961-e1970. doi: 10.1212/WNL.0000000000006549. Epub 2018 Oct 24.

PMID: 30355700 Free PMC article. 

82. 

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume. 

Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, Gillespie NA, van der Lee SJ, Neumann A, Ahmad S, Andreassen OA, Ames D, Amin N, Arfanakis K, Bastin ME, Becker DM, Beiser AS, Beyer F, Brodaty H, Bryan RN, Bülow R, Dale AM, De Jager PL, Deary IJ, DeCarli C, Fleischman DA, Gottesman RF, van der Grond J, Gudnason V, Harris TB, Homuth G, Knopman DS, Kwok JB, Lewis CE, Li S, Loeffler M, Lopez OL, Maillard P, El Marroun H, Mather KA, Mosley TH, Muetzel RL, Nauck M, Nyquist PA, Panizzon MS, Pausova Z, Psaty BM, Rice K, Rotter JI, Royle N, Satizabal CL, Schmidt R, Schofield PR, Schreiner PJ, Sidney S, Stott DJ, Thalamuthu A, Uitterlinden AG, Valdés Hernández MC, Vernooij MW, Wen W, White T, Witte AV, Wittfeld K, Wright MJ, Yanek LR, Tiemeier H, Kremen WS, Bennett DA, Jukema JW, Paus T, Wardlaw JM, Schmidt H, Sachdev PS, Villringer A, Grabe HJ, Longstreth WT, van Duijn CM, Launer LJ, Seshadri S, Ikram MA, Fornage M.

Nat Commun. 2018 Sep 26;9(1):3945. doi: 10.1038/s41467-018-06234-w.

PMID: 30258056 Free PMC article. 

83. 

Circulating Vascular Growth Factors and Magnetic Resonance Imaging Markers of Small Vessel Disease and Atrophy in Middle-Aged Adults. 

Raman MR, Himali JJ, Conner SC, DeCarli C, Vasan RS, Beiser AS, Seshadri S, Maillard P, Satizabal CL.

Stroke. 2018 Sep;49(9):2227-2229. doi: 10.1161/STROKEAHA.118.022613.

PMID: 30354979 Free PMC article. 

84. 

Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging. 

Jian X, Satizabal CL, Smith AV, Wittfeld K, Bis JC, Smith JA, Hsu FC, Nho K, Hofer E, Hagenaars SP, Nyquist PA, Mishra A, Adams HHH, Li S, Teumer A, Zhao W, Freedman BI, Saba Y, Yanek LR, Chauhan G, van Buchem MA, Cushman M, Royle NA, Bryan RN, Niessen WJ, Windham BG, DeStefano AL, Habes M, Heckbert SR, Palmer ND, Lewis CE, Eiriksdottir G, Maillard P, Mathias RA, Homuth G, Valdés-Hernández MDC, Divers J, Beiser AS, Langner S, Rice KM, Bastin ME, Yang Q, Maldjian JA, Starr JM, Sidney S, Risacher SL, Uitterlinden AG, Gudnason VG, Nauck M, Rotter JI, Schreiner PJ, Boerwinkle E, van Duijn CM, Mazoyer B, von Sarnowski B, Gottesman RF, Levy D, Sigurdsson S, Vernooij MW, Turner ST, Schmidt R, Wardlaw JM, Psaty BM, Mosley TH, DeCarli CS, Saykin AJ, Bowden DW, Becker DM, Deary IJ, Schmidt H, Kardia SLR, Ikram MA, Debette S, Grabe HJ, Longstreth WT Jr, Seshadri S, Launer LJ, Fornage M; neuroCHARGE Working Group.

Stroke. 2018 Aug;49(8):1812-1819. doi: 10.1161/STROKEAHA.118.020689.

PMID: 30002152 Free PMC article. 

85. 

Vascular disease and cerebral amyloid deposition. 

Lopez OL, Maillard P.

Neurology. 2018 Apr 3;90(14):635-636. doi: 10.1212/WNL.0000000000005242. Epub 2018 Mar 16.

PMID: 29549219 No abstract available. 

86. 

Age-related white matter integrity differences in oldest-old without dementia. 

Bennett IJ, Greenia DE, Maillard P, Sajjadi SA, DeCarli C, Corrada MM, Kawas CH.

Neurobiol Aging. 2017 Aug;56:108-114. doi: 10.1016/j.neurobiolaging.2017.04.013. Epub 2017 Apr 26.

PMID: 28527525 Free PMC article. 

87. 

Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury. 

Maillard P, Mitchell GF, Himali JJ, Beiser A, Fletcher E, Tsao CW, Pase MP, Satizabal CL, Vasan RS, Seshadri S, DeCarli C.

Stroke. 2017 Jun;48(6):1567-1573. doi: 10.1161/STROKEAHA.116.016321. Epub 2017 May 4.

PMID: 28473633 Free PMC article. 

88. 

Thrombolysis for acute ischemic stroke in patients with leukoaraiosis: Caution needed. 

Streifler J, Maillard P.

Neurology. 2017 Feb 14;88(7):612-613. doi: 10.1212/WNL.0000000000003620. Epub 2017 Jan 27.

PMID: 28130471 No abstract available. 

89. 

Independent value added by diffusion MRI for prediction of cognitive function in older adults. 

Scott JA, Tosun D, Braskie MN, Maillard P, Thompson PM, Weiner M, DeCarli C, Carmichael OT; ADNI.

Neuroimage Clin. 2017 Jan 25;14:166-173. doi: 10.1016/j.nicl.2017.01.026. eCollection 2017.

PMID: 28180075 Free PMC article. 

90. 

Cerebral amyloid is associated with greater white-matter hyperintensity accrual in cognitively normal older adults. 

Scott JA, Braskie MN, Tosun D, Maillard P, Thompson PM, Weiner M, DeCarli C, Carmichael OT; ADNI.

Neurobiol Aging. 2016 Dec;48:48-52. doi: 10.1016/j.neurobiolaging.2016.08.014. Epub 2016 Aug 24.

PMID: 27639120 Free PMC article. 

91. 

β-amyloid, hippocampal atrophy and their relation to longitudinal brain change in cognitively normal individuals. 

Fletcher E, Villeneuve S, Maillard P, Harvey D, Reed B, Jagust W, DeCarli C.

Neurobiol Aging. 2016 Apr;40:173-180. doi: 10.1016/j.neurobiolaging.2016.01.133. Epub 2016 Feb 22.

PMID: 26973117 Free PMC article. 

92. 

Effects of Arterial Stiffness on Brain Integrity in Young Adults From the Framingham Heart Study. 

Maillard P, Mitchell GF, Himali JJ, Beiser A, Tsao CW, Pase MP, Satizabal CL, Vasan RS, Seshadri S, DeCarli C.

Stroke. 2016 Apr;47(4):1030-6. doi: 10.1161/STROKEAHA.116.012949. Epub 2016 Mar 10.

PMID: 26965846 Free PMC article. 

93. 

Association of Aortic Stiffness With Cognition and Brain Aging in Young and Middle-Aged Adults: The Framingham Third Generation Cohort Study. 

Pase MP, Himali JJ, Mitchell GF, Beiser A, Maillard P, Tsao C, Larson MG, DeCarli C, Vasan RS, Seshadri S.

Hypertension. 2016 Mar;67(3):513-9. doi: 10.1161/HYPERTENSIONAHA.115.06610. Epub 2016 Jan 11.

PMID: 26754644 Free PMC article. 

94. 

Guidelines for reporting methodological challenges and evaluating potential bias in dementia research. 

Weuve J, Proust-Lima C, Power MC, Gross AL, Hofer SM, Thiébaut R, Chêne G, Glymour MM, Dufouil C; MELODEM Initiative.

Alzheimers Dement. 2015 Sep;11(9):1098-109. doi: 10.1016/j.jalz.2015.06.1885.

PMID: 26397878 Free PMC article. Review. 

95. 

Magnetic resonance imaging in Alzheimer's Disease Neuroimaging Initiative 2. 

Jack CR Jr, Barnes J, Bernstein MA, Borowski BJ, Brewer J, Clegg S, Dale AM, Carmichael O, Ching C, DeCarli C, Desikan RS, Fennema-Notestine C, Fjell AM, Fletcher E, Fox NC, Gunter J, Gutman BA, Holland D, Hua X, Insel P, Kantarci K, Killiany RJ, Krueger G, Leung KK, Mackin S, Maillard P, Malone IB, Mattsson N, McEvoy L, Modat M, Mueller S, Nosheny R, Ourselin S, Schuff N, Senjem ML, Simonson A, Thompson PM, Rettmann D, Vemuri P, Walhovd K, Zhao Y, Zuk S, Weiner M.

Alzheimers Dement. 2015 Jul;11(7):740-56. doi: 10.1016/j.jalz.2015.05.002.

PMID: 26194310 Free PMC article. 

96. 

Glucose indices are associated with cognitive and structural brain measures in young adults. 

Weinstein G, Maillard P, Himali JJ, Beiser AS, Au R, Wolf PA, Seshadri S, DeCarli C.

Neurology. 2015 Jun 9;84(23):2329-37. doi: 10.1212/WNL.0000000000001655. Epub 2015 May 6.

PMID: 25948725 Free PMC article. 

97. 

Cooccurrence of vascular risk factors and late-life white-matter integrity changes. 

Maillard P, Carmichael OT, Reed B, Mungas D, DeCarli C.

Neurobiol Aging. 2015 Apr;36(4):1670-1677. doi: 10.1016/j.neurobiolaging.2015.01.007. Epub 2015 Jan 14.

PMID: 25666995 Free PMC article. 

98. 

Plasma β-amyloid and MRI markers of cerebral small vessel disease: Three-City Dijon study. 

Kaffashian S, Tzourio C, Soumaré A, Dufouil C, Zhu Y, Crivello F, Maillard P, Schraen-Maschke S, Mazoyer B, Buée L, Debette S.

Neurology. 2014 Nov 25;83(22):2038-45. doi: 10.1212/WNL.0000000000001038. Epub 2014 Oct 29.

PMID: 25355827 

99. 

White matter hyperintensities and their penumbra lie along a continuum of injury in the aging brain. 

Maillard P, Fletcher E, Lockhart SN, Roach AE, Reed B, Mungas D, DeCarli C, Carmichael OT.

Stroke. 2014 Jun;45(6):1721-6. doi: 10.1161/STROKEAHA.113.004084. Epub 2014 Apr 29.

PMID: 24781079 Free PMC article. Clinical Trial. 

100. 

FLAIR and diffusion MRI signals are independent predictors of white matter hyperintensities. 

Maillard P, Carmichael O, Harvey D, Fletcher E, Reed B, Mungas D, DeCarli C.

AJNR Am J Neuroradiol. 2013 Jan;34(1):54-61. doi: 10.3174/ajnr.A3146. Epub 2012 Jun 14.

PMID: 22700749 Free PMC article. 

101. 

Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study. 

Maillard P, Seshadri S, Beiser A, Himali JJ, Au R, Fletcher E, Carmichael O, Wolf PA, DeCarli C.

Lancet Neurol. 2012 Dec;11(12):1039-47. doi: 10.1016/S1474-4422(12)70241-7. Epub 2012 Nov 2.

PMID: 23122892 Free PMC article. 

102. 

The contributions of MRI-based measures of gray matter, white matter hyperintensity, and white matter integrity to late-life cognition. 

He J, Wong VS, Fletcher E, Maillard P, Lee DY, Iosif AM, Singh B, Martinez O, Roach AE, Lockhart SN, Beckett L, Mungas D, Farias ST, Carmichael O, DeCarli C.

AJNR Am J Neuroradiol. 2012 Oct;33(9):1797-803. doi: 10.3174/ajnr.A3048. Epub 2012 Apr 26.

PMID: 22538073 Free PMC article. 

103. 

Plasma long-chain omega-3 fatty acids and atrophy of the medial temporal lobe. 

Samieri C, Maillard P, Crivello F, Proust-Lima C, Peuchant E, Helmer C, Amieva H, Allard M, Dartigues JF, Cunnane SC, Mazoyer BM, Barberger-Gateau P.

Neurology. 2012 Aug 14;79(7):642-50. doi: 10.1212/WNL.0b013e318264e394. Epub 2012 Aug 1.

PMID: 22855869 

104. 

Coevolution of white matter hyperintensities and cognition in the elderly. 

Maillard P, Carmichael O, Fletcher E, Reed B, Mungas D, DeCarli C.

Neurology. 2012 Jul 31;79(5):442-8. doi: 10.1212/WNL.0b013e3182617136. Epub 2012 Jul 18.

PMID: 22815562 Free PMC article. 

105. 

Episodic memory function is associated with multiple measures of white matter integrity in cognitive aging. 

Lockhart SN, Mayda AB, Roach AE, Fletcher E, Carmichael O, Maillard P, Schwarz CG, Yonelinas AP, Ranganath C, Decarli C.

Front Hum Neurosci. 2012 Mar 16;6:56. doi: 10.3389/fnhum.2012.00056. eCollection 2012.

PMID: 22438841 Free PMC article. 

106. 

White matter hyperintensity penumbra. 

Maillard P, Fletcher E, Harvey D, Carmichael O, Reed B, Mungas D, DeCarli C.

Stroke. 2011 Jul;42(7):1917-22. doi: 10.1161/STROKEAHA.110.609768. Epub 2011 Jun 2.

PMID: 21636811 Free PMC article. 

107. 

Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. 

Fornage M, Debette S, Bis JC, Schmidt H, Ikram MA, Dufouil C, Sigurdsson S, Lumley T, DeStefano AL, Fazekas F, Vrooman HA, Shibata DK, Maillard P, Zijdenbos A, Smith AV, Gudnason H, de Boer R, Cushman M, Mazoyer B, Heiss G, Vernooij MW, Enzinger C, Glazer NL, Beiser A, Knopman DS, Cavalieri M, Niessen WJ, Harris TB, Petrovic K, Lopez OL, Au R, Lambert JC, Hofman A, Gottesman RF, Garcia M, Heckbert SR, Atwood LD, Catellier DJ, Uitterlinden AG, Yang Q, Smith NL, Aspelund T, Romero JR, Rice K, Taylor KD, Nalls MA, Rotter JI, Sharrett R, van Duijn CM, Amouyel P, Wolf PA, Gudnason V, van der Lugt A, Boerwinkle E, Psaty BM, Seshadri S, Tzourio C, Breteler MM, Mosley TH, Schmidt R, Longstreth WT, DeCarli C, Launer LJ.

Ann Neurol. 2011 Jun;69(6):928-39. doi: 10.1002/ana.22403.

PMID: 21681796 Free PMC article. 

108. 

Longitudinal neuroimaging correlates of subjective memory impairment: 4-year prospective community study. 

Stewart R, Godin O, Crivello F, Maillard P, Mazoyer B, Tzourio C, Dufouil C.

Br J Psychiatry. 2011 Mar;198(3):199-205. doi: 10.1192/bjp.bp.110.078683.

PMID: 21357878 

109. 

Antihypertensive treatment and change in blood pressure are associated with the progression of white matter lesion volumes: the Three-City (3C)-Dijon Magnetic Resonance Imaging Study. 

Godin O, Tzourio C, Maillard P, Mazoyer B, Dufouil C.

Circulation. 2011 Jan 25;123(3):266-73. doi: 10.1161/CIRCULATIONAHA.110.961052. Epub 2011 Jan 10.

PMID: 21220733 

110. 

Headache, migraine, and structural brain lesions and function: population based Epidemiology of Vascular Ageing-MRI study. 

Kurth T, Mohamed S, Maillard P, Zhu YC, Chabriat H, Mazoyer B, Bousser MG, Dufouil C, Tzourio C.

BMJ. 2011 Jan 18;342:c7357. doi: 10.1136/bmj.c7357.

PMID: 21245119 Free PMC article. 

111. 

Joint effect of white matter lesions and hippocampal volumes on severity of cognitive decline: the 3C-Dijon MRI study. 

Godin O, Tzourio C, Rouaud O, Zhu Y, Maillard P, Pasquier F, Crivello F, Alpérovitch A, Mazoyer B, Dufouil C.

J Alzheimers Dis. 2010;20(2):453-63. doi: 10.3233/JAD-2010-1389.

PMID: 20164560 

112. 

Apolipoprotein E genotype is related to progression of white matter lesion load. 

Godin O, Tzourio C, Maillard P, Alpérovitch A, Mazoyer B, Dufouil C.

Stroke. 2009 Oct;40(10):3186-90. doi: 10.1161/STROKEAHA.109.555839. Epub 2009 Jul 30.

PMID: 19644067 

113. 

Cerebral white matter lesions are associated with the risk of stroke but not with other vascular events: the 3-City Dijon Study. 

Buyck JF, Dufouil C, Mazoyer B, Maillard P, Ducimetière P, Alpérovitch A, Bousser MG, Kurth T, Tzourio C.

Stroke. 2009 Jul;40(7):2327-31. doi: 10.1161/STROKEAHA.109.548222. Epub 2009 May 14.

PMID: 19443799 

114. 

White matter lesions volume and motor performances in the elderly. 

Soumaré A, Elbaz A, Zhu Y, Maillard P, Crivello F, Tavernier B, Dufouil C, Mazoyer B, Tzourio C.

Ann Neurol. 2009 Jun;65(6):706-15. doi: 10.1002/ana.21674.

PMID: 19557865 

115. 

Longitudinal follow-up of individual white matter hyperintensities in a large cohort of elderly. 

Maillard P, Crivello F, Dufouil C, Tzourio-Mazoyer N, Tzourio C, Mazoyer B.

Neuroradiology. 2009 Apr;51(4):209-20. doi: 10.1007/s00234-008-0489-0. Epub 2009 Jan 13.

PMID: 19139875 

116. 

Association of white-matter lesions with brain atrophy markers: the three-city Dijon MRI study. 

Godin O, Maillard P, Crivello F, Alpérovitch A, Mazoyer B, Tzourio C, Dufouil C.

Cerebrovasc Dis. 2009;28(2):177-84. doi: 10.1159/000226117. Epub 2009 Jun 25.

PMID: 19556771 

117. 

Neuroimaging correlates of subjective memory deficits in a community population. 

Stewart R, Dufouil C, Godin O, Ritchie K, Maillard P, Delcroix N, Crivello F, Mazoyer B, Tzourio C.

Neurology. 2008 Apr 29;70(18):1601-7. doi: 10.1212/01.wnl.0000310982.99438.54.

PMID: 18443310 

118. 

White matter lesions as a predictor of depression in the elderly: the 3C-Dijon study. 

Godin O, Dufouil C, Maillard P, Delcroix N, Mazoyer B, Crivello F, Alpérovitch A, Tzourio C.

Biol Psychiatry. 2008 Apr 1;63(7):663-9. doi: 10.1016/j.biopsych.2007.09.006. Epub 2007 Oct 30.

PMID: 17977521 

119. 

An automated procedure for the assessment of white matter hyperintensities by multispectral (T1, T2, PD) MRI and an evaluation of its between-centre reproducibility based on two large community databases. 

Maillard P, Delcroix N, Crivello F, Dufouil C, Gicquel S, Joliot M, Tzourio-Mazoyer N, Alpérovitch A, Tzourio C, Mazoyer B.

Neuroradiology. 2008 Jan;50(1):31-42. doi: 10.1007/s00234-007-0312-3. Epub 2007 Oct 16.

PMID: 17938898